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Dufresne received a BFA in 1991 from the Kansas City Art Institute and an MFA from the Tyler School of Art, Temple University, Philadelphia, in 1998.
She has shown work internationally in exhibitions including Greater New York at P.S.1 Contemporary Art Center, the 2005 ARCO Art Fair for Galeria Marta Cervera in Madrid, Miracle on Franklin Street at GV/AS in Brooklyn and The Triumph of Painting at the Saatchi Gallery in London.
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